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KCNMB3 Protein (AA 82-207) (His tag)

KCNMB3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN5853863
  • Target See all KCNMB3 Proteins
    KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 82-207
    Origin
    Human
    Source
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This KCNMB3 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSKPFMLSI QREESTCTAI HTDIMDDWLD CAFTCGVHCH GQGKYPCLQV FVNLSHPGQK ALLHYNEEAV QINPKCFYTP KCHQDRNDLL NSALDIKEFF DHKNGTPFSC FYSPASQSED VILIKKYDQ
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product KCNMB3 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Denatured

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M uREA, 10 % glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))
    Alternative Name
    KCNMB3 (KCNMB3 Products)
    Synonyms
    KCNMB3 Protein, BKBETA3 Protein, HBETA3 Protein, KCNMB2 Protein, KCNMBL Protein, SLOBETA3 Protein, EG435726 Protein, Gm5707 Protein, potassium calcium-activated channel subfamily M regulatory beta subunit 3 Protein, potassium channel subfamily M regulatory beta subunit 3 S homeolog Protein, potassium large conductance calcium-activated channel, subfamily M beta member 3 Protein, potassium large conductance calcium-activated channel, subfamily M, beta member 3 Protein, KCNMB3 Protein, kcnmb3.S Protein, Kcnmb3 Protein
    Background
    The KCNMB3 is one of a family of four auxiliary beta subunits found in the mammalian genome that associate with Slo1 alpha subunits and regulate BK channel function. In humans, the KCNMB3 gene contains four N-terminal alternative exons that produce four functionally distinct beta3 subunits, beta3a-d. Three variants, beta3a-c, exhibit kinetically distinct inactivation behaviors. Recombinant human KCNMB3 fused to His-tag at N-terminus, was expressed in E.coli.
    Molecular Weight
    16.8kDa (149aa)
    NCBI Accession
    NP_055222
    UniProt
    Q9NPA1
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