KCNMB3 Protein (AA 82-207) (His tag)
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- Target See all KCNMB3 Proteins
- KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 82-207
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This KCNMB3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSKPFMLSI QREESTCTAI HTDIMDDWLD CAFTCGVHCH GQGKYPCLQV FVNLSHPGQK ALLHYNEEAV QINPKCFYTP KCHQDRNDLL NSALDIKEFF DHKNGTPFSC FYSPASQSED VILIKKYDQ
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product KCNMB3 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))
- Alternative Name
- KCNMB3 (KCNMB3 Products)
- Synonyms
- KCNMB3 Protein, BKBETA3 Protein, HBETA3 Protein, KCNMB2 Protein, KCNMBL Protein, SLOBETA3 Protein, EG435726 Protein, Gm5707 Protein, potassium calcium-activated channel subfamily M regulatory beta subunit 3 Protein, potassium channel subfamily M regulatory beta subunit 3 S homeolog Protein, potassium large conductance calcium-activated channel, subfamily M beta member 3 Protein, potassium large conductance calcium-activated channel, subfamily M, beta member 3 Protein, KCNMB3 Protein, kcnmb3.S Protein, Kcnmb3 Protein
- Background
- The KCNMB3 is one of a family of four auxiliary beta subunits found in the mammalian genome that associate with Slo1 alpha subunits and regulate BK channel function. In humans, the KCNMB3 gene contains four N-terminal alternative exons that produce four functionally distinct beta3 subunits, beta3a-d. Three variants, beta3a-c, exhibit kinetically distinct inactivation behaviors. Recombinant human KCNMB3 fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 16.8kDa (149aa)
- NCBI Accession
- NP_055222
- UniProt
- Q9NPA1
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