SERPINE2 Protein (AA 20-397) (His tag)

Catalog No. ABIN5854648

Product Details

Target: SERPINE2 (serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2))

Protein Type: Recombinant

Protein Characteristics: AA 20-397

Origin: Mouse

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This SERPINE2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: SQFNSLSLEE LGSNTGIQVF NQIIKSRPHE NVVVSPHGIA SILGMLQLGA DGKTKKQLST VMRYNVNGVG KVLKKINKAI VSKKNKDIVT VANAVFLRNG FKMEVPFAVR NKDVFQCEVQ NVNFQDPASA SESINFWVKN ETRGMIDNLL SPNLIDGALT RLVLVNAVYF KGLWKSRFQP ESTKKRTFVA GDGKSYQVPM LAQLSVFRSG STRTPNGLWY NFIELPYHGE SISMLIALPT ESSTPLSAII PHITTKTIDS WMNTMVPKRM QLVLPKFTAV AQTDLKEPLK ALGITEMFEP SKANFTKITR SESLHVSHIL QKAKIEVSED GTKASAATTA ILIARSSPPW FIVDRPFLFS IRHNPTGAIL FLGQVNKPLE HHHHHH

Purity: > 95 % by SDS - PAGE

Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: SERPINE2 (serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2))

Alternative Name: Serpine2 (SERPINE2 Products)

Synonyms: GDN Protein, GDNPF Protein, PI-7 Protein, PI7 Protein, PN-1 Protein, PN1 Protein, PNI Protein, SERPINE2 Protein, MGC143011 Protein, Gdnpn1 Protein, Pn-1 Protein, Spin4 Protein, B230326M24Rik Protein, PAI-1 Protein, Spi4 Protein, zgc:55929 Protein, serpin family E member 2 Protein, serine (or cysteine) peptidase inhibitor, clade E, member 2 Protein, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 Protein, SERPINE2 Protein, serpine2 Protein, Serpine2 Protein

Background: Serpine2, as known as glia-derived nexin, is a member of the Serpin superfamily of the serine protease inhibitors. This protein is a potent inhibitor of thrombin, plasmin and plasminogen activators. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuron-like cells. Also, it is over expression in mice leads to progressive neuronal and motor dysfunction in these animals. Recombinant mouse Serpine2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques

Molecular Weight: 42.9kDa (386aa) 40-57kDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_033281

UniProt: Q07235