TACSTD2 Protein (AA 31-274) (His tag)
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- Target See all TACSTD2 Proteins
- TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 31-274
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This TACSTD2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPQDNCTCP TNKMTVCSPD GPGGRCQCRA LGSGMAVDCS TLTSKCLLLK ARMSAPKNAR TLVRPSEHAL VDNDGLYDPD CDPEGRFKAR QCNQTSVCWC VNSVGVRRTD KGDLSLRCDE LVRTHHILID LRHRPTAGAF NHSDLDAELR RLFRERYRLH PKFVAAVHYE QPTIQIELRQ NTSQKAAGDV DIGDAAYYFE RDIKGESLFQ GRGGLDLRVR GEPLQVERTL IYYLDEIPPK FSMKRLTHHH HHH
- Purity
- > 95 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product TACSTD2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
- Alternative Name
- TACSTD2 (TACSTD2 Products)
- Synonyms
- EGP-1 Protein, EGP1 Protein, GA733-1 Protein, GA7331 Protein, GP50 Protein, M1S1 Protein, TROP2 Protein, C80403 Protein, Ly97 Protein, Prp1 Protein, tumor associated calcium signal transducer 2 Protein, tumor-associated calcium signal transducer 2 Protein, TACSTD2 Protein, Tacstd2 Protein
- Background
- TACSTD2, also known as tumor-associated calcium signal transducer 2, is an identified cell surface glycoprotein highly expressed by human carcinomas. It is detected in normal kidney, lung, ovary and testis, similarly to the human gene. It is undetectable in undifferentiated spindle cell carcinomas, this suggests a preferential expression at early stages of tumor progression. Its inhibition suppresses the proliferation and invasion of laryngeal carcinoma cells via the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway. Recombinant human TACSTD2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 28.6kDa (253aa) 28-40kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_002344
- UniProt
- P09758
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