ADH1A Protein (AA 1-375) (His tag)

Catalog No. ABIN5854753

Product Details

Target: ADH1A (Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A))

Protein Type: Recombinant

Protein Characteristics: AA 1-375

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This ADH1A protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MSTAGKVIKC KAAVLWELKK PFSIEEVEVA PPKAHEVRIK MVAVGICGTD DHVVSGTMVT PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLAIPQCGK CRICKNPESN YCLKNDVSNP QGTLQDGTSR FTCRRKPIHH FLGISTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG YGSAVNVAKV TPGSTCAVFG LGGVGLSAIM GCKAAGAARI IAVDINKDKF AKAKELGATE CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPDSQ NLSMNPMLLL TGRTWKGAIL GGFKSKECVP KLVADFMAKK FSLDALITHV LPFEKINEGF DLLHSGKSIR TILMFHHHHH H

Purity: > 95 % by SDS - PAGE

Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: ADH1A (Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A))

Alternative Name: ADH1A (ADH1A Products)

Synonyms: ADC1 Protein, ADH1 Protein, ADH Protein, ARVP Protein, AVP-NPII Protein, AVRP Protein, VP Protein, adh-1 Protein, ADH-AA Protein, AI194826 Protein, Adh-1 Protein, Adh-1-t Protein, Adh-1e Protein, Adh-1t Protein, Adh-3e Protein, Adh1-e Protein, Adh1-t Protein, Adh1tl Protein, Adh3-e Protein, Adh Protein, Adh1a Protein, Adh1c Protein, Adh1 Protein, Dvir\\Adh Protein, Dvir\\GJ18208 Protein, GJ18208 Protein, dvir_GLEANR_2771 Protein, ADH-1 Protein, ADH1B Protein, alcohol dehydrogenase ADH1 Protein, alcohol dehydrogenase 1A (class I), alpha polypeptide Protein, arginine vasopressin Protein, alcohol dehydrogenase 1 Protein, alcohol dehydrogenase 1A Protein, alcohol dehydrogenase 1 (class I) Protein, Alcohol dehydrogenase 1 Protein, alcohol dehydrogenase 1C (class I), gamma polypeptide Protein, ADH1 Protein, ADH1A Protein, AVP Protein, adh1 Protein, LOC744064 Protein, Adh1 Protein, Dvir\Adh1 Protein, ADH1C Protein

Background: ADH1A, also known as alcohol dehydrogenase 1A, belongs to the alcohol dehydrogenase family. It plays a key role in hepatic alcohol catabolism. Its activity may be the cause of disorders in metabolic pathways that use these isoenzymes and could increase the concentration of acetaldehyde, which is cancerogenic substance. It is positively correlated with those of CDR1, CDR2 and FLU1. Recombinant human ADH1A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 40.6kDa (381aa) 40-57kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_000658

UniProt: P07327