CD236/GYPC Protein (AA 1-57) (His tag)
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- Target See all CD236/GYPC (GYPC) Proteins
- CD236/GYPC (GYPC) (Glycophorin C (GYPC))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-57
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CD236/GYPC protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPMWSTRSP NSTAWPLSLE PDPGMASAST TMHTTTIAEP DPGMSGWPDG RMETSTPTIM HHHHHH
- Purity
- > 95 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product GYPC Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- CD236/GYPC (GYPC) (Glycophorin C (GYPC))
- Alternative Name
- GYPC (GYPC Products)
- Synonyms
- GPC Protein, glpc Protein, 0610037F22Rik Protein, Cd236r Protein, CD236 Protein, CD236R Protein, GE Protein, GPD Protein, GYPD Protein, PAS-2 Protein, PAS-2' Protein, glycophorin C a Protein, glycophorin C (Gerbich blood group) Protein, Glycophorin-C Protein, glycophorin C Protein, gpca Protein, GYPC Protein, glpc Protein, Gypc Protein
- Target Type
- Viral Protein
- Background
- GYPC, also known as glycophorin-C isoform 1, is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. Recombinant human GYPC protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 7.2kDa (66aa) 18-28KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_002092
- UniProt
- P04921
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