KIR2DL5A Protein (AA 22-238) (hIgG-His-tag)
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- Target See all KIR2DL5A Proteins
- KIR2DL5A (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-238
- Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This KIR2DL5A protein is labelled with hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPHEGGQDK PLLSAWPSAV VPRGGHVTLL CRSRLGFTIF SLYKEDGVPV PELYNKIFWK SILMGPVTPA HAGTYRCRGS HPRSPIEWSA PSNPLVIVVT GLFGKPSLSA QPGPTVRTGE NVTLSCSSRS SFDMYHLSRE GRAHEPRLPA VPSVNGTFQA DFPLGPATHG GTYTCFGSLH DSPYEWSDPS DPLLVSVTGN SSSSSSSPTE PSSKTGIRRH VEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS RDELTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGKHHHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product KIR2DL5A Protein
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Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) (AA 22-240) protein (His-Avi Tag)
KIR2DL5A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) (AA 22-240) protein (His-Avi Tag,Biotin)KIR2DL5A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) (AA 22-238) protein (His tag)Crystallography grade KIR2DL5A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) (AA 260-375) protein (His tag)Crystallography grade KIR2DL5A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) (AA 22-375) protein (rho-1D4 tag)Crystallography grade KIR2DL5A Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- KIR2DL5A (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A))
- Alternative Name
- KIR2DL5A (KIR2DL5A Products)
- Synonyms
- CD158F Protein, KIR2DL5 Protein, KIR2DL5.1 Protein, KIR2DL5.3 Protein, KIR2DL5B Protein, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A Protein, KIR2DL5A Protein
- Background
- KIR2DL5A, also known as killer cell immunoglobulin-like receptor 2DL5A, is a type I transmembrane glycoprotein that belongs to the killer cell Ig-like receptor (KIR) family. It is detected on the cell surface as a monomer that, upon tyrosine phosphorylation, recruits the Src homology region 2-containing protein tyrosine phosphatase-2, It is thus an inhibitory receptor gathering a combination of genetic, structural, and functional features unique among KIR, which suggests that it plays a specialized role in innate immunity. Recombinant human KIR2DL5A, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 50.5kDa (459aa) 50-70kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_065396
- UniProt
- Q8N109
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