SH2D1B Protein (AA 1-132) (His tag)
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- Target See all SH2D1B Proteins
- SH2D1B (SH2 Domain Containing 1B (SH2D1B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-132
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This SH2D1B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPMDLPYYH GRLTKQDCET LLLKEGVDGN FLLRDSESIP GVLCLCVSFK NIVYTYRIFR EKHGYYRIQT AEGSPKQVFP SLKELISKFE KPNQGMVVHL LKPIKRTSPS LRWRGLKLEL ETFVNSNSDY VDVLPHHHHH H
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product SH2D1B Protein
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SH2 Domain Containing 1B (SH2D1B) (AA 1-132) protein (GST tag)
SH2D1B Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
SH2 Domain Containing 1B (SH2D1B) (AA 54-132) protein (GST tag)SH2D1B Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
SH2 Domain Containing 1B (SH2D1B) (AA 1-132) protein (Strep Tag)Crystallography grade SH2D1B Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
SH2 Domain Containing 1B (SH2D1B) (AA 1-132) protein (Strep Tag)Crystallography grade SH2D1B Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
SH2 Domain Containing 1B (SH2D1B) protein (Myc-DYKDDDDK Tag)SH2D1B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 20 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- SH2D1B (SH2 Domain Containing 1B (SH2D1B))
- Alternative Name
- SH2D1B (SH2D1B Products)
- Synonyms
- EAT2 Protein, Sh2d1b1 Protein, RGD1563935 Protein, SH2 domain containing 1B Protein, SH2D1B Protein, Sh2d1b Protein
- Background
- SH2D1B, also known as SH2 domain-containing protein 1B, is one of the proteins which activate NK cells. It plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells. Two isoforms of the human protein are produced by alternative splicing. Recombinant human SH2D1B protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 16.4kDa (141aa) 18-28KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_444512
- UniProt
- O14796
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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