FCGR3B Protein (AA 21-200) (His tag)
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- Target See all FCGR3B Proteins
- FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-200
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This FCGR3B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- EDLPKAVVFL EPQWYSVLEK DSVTLKCQGA YSPEDNSTQW FHNENLISSQ ASSYFIDAAT VNDSGEYRCQ TNLSTLSDPV QLEVHIGWLL LQAPRWVFKE EDPIHLRCHS WKNTALHKVT YLQNGKDRKY FHHNSDFHIP KATLKDSGSY FCRGLVGSKN VSSETVNITI TQGLAVSTIS VEHHHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product FCGR3B Protein
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Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) (AA 17-200) protein (His-Avi Tag)
FCGR3B Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) (AA 17-200) protein (His tag)FCGR3B Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) protein (His-Avi Tag,Biotin)FCGR3B Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) (Active) protein (Biotin)FCGR3B Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) (AA 17-200) protein (His tag)Crystallography grade FCGR3B Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) (AA 17-208) (Active) protein (His tag)FCGR3B Origin: Cynomolgus Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B) (AA 17-208) (Active) protein (His tag,AVI tag,Biotin)FCGR3B Origin: Cynomolgus Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- FCGR3B (Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))
- Alternative Name
- FCGR3B (FCGR3B Products)
- Synonyms
- CD16 Protein, CD16b Protein, FCG3 Protein, FCGR3 Protein, FCR-10 Protein, FCRIII Protein, FCRIIIb Protein, FcRIII Protein, Fc fragment of IgG receptor IIIb Protein, Fc receptor, IgG, low affinity III Protein, Fc fragment of IgG receptor IIIa Protein, Fc-gamma RIII Protein, FCGR3B Protein, Fcgr3 Protein, FCGR3A Protein, FCGR3 Protein
- Background
- FCGR3B, also known as low affinity immunoglobulin gamma Fc region receptor III-B isoform 2, is a member of Ig super family. It encodes a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed constitutively by neutrophils and after gamma-interferon stimulation by eosinophils. This protein binds to complex or aggregated IgG and monomeric IgG. Unlike III-A, it cannot mediate antibody-dependent cytotoxicity and phagocytosis. It can be a trap of immune complexes in peripheral blood circulation that does not activate neutrophils. Recombinant human FCGR3B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 21.4kDa (188aa) 28-40kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_000561
- UniProt
- O75015
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