LILRA1 Protein (AA 17-461) (His tag,AVI tag,Biotin)

Catalog No. ABIN5954999

Product Details

Target: LILRA1 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 1 (LILRA1))

Protein Type: Recombinant

Biological Activity: Active

Protein Characteristics: AA 17-461

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This LILRA1 protein is labelled with His tag,AVI tag,Biotin.

Sequence: AA 17-461

Specificity: Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

Purity: >90 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Comment:

Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Target Details

Target: LILRA1 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 1 (LILRA1))

Alternative Name: LILRA1 (LILRA1 Products)

Synonyms: CD85I Protein, LIR-6 Protein, LIR6 Protein, leukocyte immunoglobulin like receptor A1 Protein, LILRA1 Protein

Background: Leukocyte immunoglobulin-like receptors (LILRs) are inhibitory, stimulatory or soluble receptors encoded within the leukocyte receptor complex. Some LILRs are extensively polymorphic, and exhibit evidence for balancing selection and association with disease susceptibility. LILRA1 (LIR-6) can recognize MHC (major histocompatibility complex) class I or class I-like molecules, and high levels of sequence similarity among LILRA1, LILRA2 (ILT1), LILRA3 (ILT6) and LILRB1/B2.

Molecular Weight: 52.2 kDa