CHCHD3 Protein (AA 1-227) (His tag)

Catalog No. ABIN6387316

Product Details

Target: CHCHD3 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 3 (CHCHD3))

Protein Type: Recombinant

Protein Characteristics: AA 1-227

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CHCHD3 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGGTTST RRVTFEADEN ENITVVKGIR LSENVIDRMK ESSPSGSKSQ RYSGAYGASV SDEELKRRVA EELALEQAKK ESEDQKRLKQ AKELDRERAA ANEQLTRAIL RERICSEEER AKAKHLARQL EEKDRVLKKQ DAFYKEQLAR LEERSSEFYR VTTEQYQKAA EEVEAKFKRY ESHPVCADLQ AKILQCYREN THQTLKCSAL ATQYMHCVNH AKQSMLEKGG

Purity: > 80 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: CHCHD3 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 3 (CHCHD3))

Alternative Name: CHCHD3 (CHCHD3 Products)

Synonyms: MINOS3 Protein, PPP1R22 Protein, 0610041L09Rik Protein, 1700039J09Rik Protein, AW558177 Protein, plxna4 Protein, FLJ20420 Protein, wu:fe23h05 Protein, zgc:111837 Protein, si:rp71-18a24.1 Protein, MGC80265 Protein, MGC88973 Protein, coiled-coil-helix-coiled-coil-helix domain containing 3 Protein, coiled-coil-helix-coiled-coil-helix domain containing 3a Protein, coiled-coil-helix-coiled-coil-helix domain containing 3 L homeolog Protein, CHCHD3 Protein, Chchd3 Protein, chchd3a Protein, chchd3.L Protein, chchd3 Protein, LOC100229580 Protein

Background: Coiled-coil-helix-coiled-coil-helix domain containing protein 3, also known as CHCHD3, is required for maintenance of mitochondrial crista integrity and mitochondrial function. This protein may act as a scaffolding protein that stabilizes protein complexes involved in crista architecture and protein import. It has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Recombinant human CHCHD3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 28.5 kDa (250aa) confirmed by MALDI-TOF

NCBI Accession: NP_060282

UniProt: Q9NX63