EXOSC1 Protein (AA 1-195) (His tag)
-
- Target See all EXOSC1 Proteins
- EXOSC1 (Exosome Component 1 (EXOSC1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-195
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This EXOSC1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMAPPVRY CIPGERLCNL EEGSPGSGTY TRHGYIFSSL AGCLMKSSEN GALPVVSVVR ETESQLLPDV GAIVTCKVSS INSRFAKVHI LYVGSMPLKN SFRGTIRKED VRATEKDKVE IYKSFRPGDI VLAKVISLGD AQSNYLLTTA ENELGVVVAH SESGIQMVPI SWCEMQCPKT HTKEFRKVAR VQPEFLQT
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product EXOSC1 Protein
-
Exosome Component 1 (EXOSC1) (AA 1-195) protein (His tag)
EXOSC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Exosome Component 1 (EXOSC1) (AA 1-195) protein (GST tag)EXOSC1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Exosome Component 1 (EXOSC1) (AA 1-195) protein (Strep Tag)Crystallography grade EXOSC1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Exosome Component 1 (EXOSC1) (AA 1-195) protein (Strep Tag)Crystallography grade EXOSC1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Exosome Component 1 (EXOSC1) protein (Myc-DYKDDDDK Tag)EXOSC1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- Target
- EXOSC1 (Exosome Component 1 (EXOSC1))
- Alternative Name
- EXOSC1 (EXOSC1 Products)
- Synonyms
- MGC86284 Protein, CGI-108 Protein, CSL4 Protein, Csl4p Protein, SKI4 Protein, Ski4p Protein, hCsl4p Protein, p13 Protein, 2610035C18Rik Protein, 2610104C07Rik Protein, 2610312F07Rik Protein, AI447561 Protein, exosome component 1 Protein, exosome component 1 L homeolog Protein, EXOSC1 Protein, exosc1.L Protein, exosc1 Protein, PTRG_05845 Protein, Exosc1 Protein
- Background
- EXOSC1 is a core component of the exosome. The mammalian exosome is required for rapid degradation of Au rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Recombinant human EXOSC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 23.8 kDa (218aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_057130
- UniProt
- Q9Y3B2
-
