PGC Protein (AA 17-388) (His tag)
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- Target See all PGC Proteins
- PGC (Pepsinogen C (PGC))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 17-388
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This PGC protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- AVVKVPLKKF KSIRETMKEK GLLGEFLRTH KYDPAWKYRF GDLSVTYEPM AYMDAAYFGE ISIGTPPQNF LVLFDTGSSN LWVPSVYCQS QACTSHSRFN PSESSTYSTN GQTFSLQYGS GSLTGFFGYD TLTVQSIQVP NQEFGLSENE PGTNFVYAQF DGIMGLAYPA LSVDEATTAM QGMVQEGALT SPVFSVYLSN QQGSSGGAVV FGGVDSSLYT GQIYWAPVTQ ELYWQIGIEE FLIGGQASGW CSEGCQAIVD TGTSLLTVPQ QYMSALLQAT GAQEDEYGQF LVNCNSIQNL PSLTFIINGV EFPLPPSSYI LSNNGYCTVG VEPTYLSSQN GQPLWILGDV FLRSYYSVYD LGNNRVGFAT AALEHHHHHH
- Purity
- > 95 % by SDS - PAGE.
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product PGC Protein
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Pepsinogen C (PGC) (AA 1-388) protein (GST tag)
PGC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Pepsinogen C (PGC) protein (His tag)PGC Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Pepsinogen C (PGC) (AA 60-388) protein (His tag)Crystallography grade PGC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Pepsinogen C (PGC) (AA 63-392) protein (His tag)Crystallography grade PGC Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- PGC (Pepsinogen C (PGC))
- Alternative Name
- PGC (PGC Products)
- Synonyms
- PEPC Protein, PGII Protein, 2210410L06Rik Protein, Upg-1 Protein, Upg1 Protein, CPGC Protein, gastricsin Protein, PG1 Protein, Pg-1 Protein, PGNC Protein, PGC Protein, Gastricsin Protein, progastricsin (pepsinogen C) Protein, progastricsin Protein, PGC Protein, Pgc Protein
- Background
- PGC, also known as gastricsin, is an aspartic proteinase that belongs to the peptidase family A1. It is synthesized in the gastric mucosa as inactive precursors. It contains a prosegment that serves to stabilize the inactive form and prevent entry of the substrate to the active site. Serum levels of PGC are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Recombinant human PGC, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques
- Molecular Weight
- 41.6kDa (380aa) 40-57kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_002621
- UniProt
- P20142
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