Kallikrein 15 Protein (AA 17-256) (His tag)

Catalog No. ABIN6388017

Product Details

Target: Kallikrein 15 (KLK15) (Kallikrein-Related Peptidase 15 (KLK15))

Protein Type: Recombinant

Protein Characteristics: AA 17-256

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This Kallikrein 15 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: ADPQDGDKLL EGDECAPHSQ PWQVALYERG RFNCGASLIS PHWVLSAAHC QSRFMRVRLG EHNLRKRDGP EQLRTTSRVI PHPRYEARSH RNDIMLLRLV QPARLNPQVR PAVLPTRCPH PGEACVVSGW GLVSHNEPGT AGSPRSQVSL PDTLHCANIS IISDTSCDKS YPGRLTNTMV CAGAEGRGAE SCEGDSGGPL VCGGILQGIV SWGDVPCDNT TKPGVYTKVC HYLEWIRETM KRNHHHHHH

Purity: > 80 % by SDS - PAGE

Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: Kallikrein 15 (KLK15) (Kallikrein-Related Peptidase 15 (KLK15))

Alternative Name: KLK15 (KLK15 Products)

Synonyms: ACO Protein, HSRNASPH Protein, kallikrein related-peptidase 15 Protein, kallikrein related peptidase 15 Protein, kallikrein-related peptidase 15 Protein, Klk15 Protein, KLK15 Protein

Background: KLK15, also known as kallikrein-15 isoform 4, is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. Also, growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In prostate cancer, it has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. Recombinant human KLK15, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 27.4kDa (249aa) 28-40kDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_059979

UniProt: Q9H2R5

Pathways: Complement System