GFRA3 Protein (AA 32-374) (hIgG-His-tag)
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- Target See all GFRA3 Proteins
- GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-374
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This GFRA3 protein is labelled with hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPDPLPTES RLMNSCLQAR RKCQADPTCS AAYHHLDSCT SSISTPLPSE EPSVPADCLE AAQQLRNSSL IGCMCHRRMK NQVACLDIYW TVHRARSLGN YELDVSPYED TVTSKPWKMN LSKLNMLKPD SDLCLKFAML CTLNDKCDRL RKAYGEACSG PHCQRHVCLR QLLTFFEKAA EPHAQGLLLC PCAPNDRGCG ERRRNTIAPN CALPPVAPNC LELRRLCFSD PLCRSRLVDF QTHCHPMDIL GTCATEQSRC LRAYLGLIGT AMTPNFVSNV NTSVALSCTC RGSGNLQEEC EMLEGFFSHN PCLTEAIAAK MRFHSQLFSQ DWPHPTFAVM AHQNENLEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH
- Purity
- > 85 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product GFRA3 Protein
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GDNF Family Receptor alpha 3 (GFRA3) (AA 32-382) protein (His tag)
GFRA3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
GDNF Family Receptor alpha 3 (GFRA3) (AA 29-379) protein (His tag)GFRA3 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
GDNF Family Receptor alpha 3 (GFRA3) (AA 1-400) protein (GST tag)GFRA3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
GDNF Family Receptor alpha 3 (GFRA3) protein (Fc Tag)GFRA3 Origin: Mouse Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE
GDNF Family Receptor alpha 3 (GFRA3) (AA 32-374) protein (His tag)Crystallography grade GFRA3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
GDNF Family Receptor alpha 3 (GFRA3) (AA 29-371) protein (His tag)Crystallography grade GFRA3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
GDNF Family Receptor alpha 3 (GFRA3) (AA 32-374) protein (His tag)GFRA3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))
- Alternative Name
- GFRA3 (GFRA3 Products)
- Synonyms
- GFRA3 Protein, GFRalpha3 Protein, Y15110 Protein, GDNF family receptor alpha 3 Protein, glial cell line derived neurotrophic factor family receptor alpha 3 Protein, Gfra3 Protein, GFRA3 Protein
- Background
- GFRA3, also known as GDNF family receptor alpha-3, is a plasma membrane glycoprotein. This protein is one of the four GDNF receptors, all of which are glycosylphosphoinositol (GPI)-linked, contain three conserved cysteine repeats, and involved survival of neurons. Also, it promotes the formation of a physical complex between GFRA/GDNFRa and the orphan tyrosin kinase receptor Ret, thereby inducing its tyrosine phosphorylation. Recombinant human GFRA3, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 65.5kDa (585aa) 70-100kDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_001487
- UniProt
- O60609
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