nectin-3 Protein (AA 58-404) (His tag)
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- Target See all nectin-3 (NECTIN3) Proteins
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 58-404
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This nectin-3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- GPIIVEPHVT AVWGKNVSLK CLIEVNETIT QISWEKIHGK SSQTVAVHHP QYGFSVQGEY QGRVLFKNYS LNDATITLHN IGFSDSGKYI CKAVTFPLGN AQSSTTVTVL VEPTVSLIKG PDSLIDGGNE TVAAICIAAT GKPVAHIDWE GDLGEMESTT TSFPNETATI ISQYKLFPTR FARGRRITCV VKHPALEKDI RYSFILDIQY APEVSVTGYD GNWFVGRKGV NLKCNADANP PPFKSVWSRL DGQWPDGLLA SDNTLHFVHP LTFNYSGVYI CKVTNSLGQR SDQKVIYISD PPTTTTLQPT IQWHPSTADI EDLATEPKKL PFPLSTLATI KDDTIATLEH HHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product NECTIN3 Protein
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Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) protein (His-Avi Tag)
NECTIN3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) protein (His-Avi Tag,Biotin)NECTIN3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) (Active) protein (Fc Tag)NECTIN3 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) (Active) protein (Fc Tag,AVI tag,Biotin)NECTIN3 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Nectin cell adhesion molecule 3 (NECTIN3) (AA 1-366) protein (GST tag)NECTIN3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Nectin cell adhesion molecule 3 (NECTIN3) (AA 59-166) protein (GST tag)NECTIN3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) protein (His tag)NECTIN3 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 20 % glycerol, 1 mM DTT.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
- Alternative Name
- NECTIN3 (NECTIN3 Products)
- Synonyms
- PVRL3 Protein, CD113 Protein, CDW113 Protein, NECTIN-3 Protein, PPR3 Protein, PRR3 Protein, PVRR3 Protein, 2610301B19Rik Protein, 3000002N23Rik Protein, 4921513D19Rik Protein, AA407785 Protein, AU016832 Protein, AW538082 Protein, nectin cell adhesion molecule 3 Protein, poliovirus receptor-related 3 Protein, Nectin3 Protein, NECTIN3 Protein, PVRL3 Protein, nectin3 Protein
- Background
- NECTIN3, also known as nectin-3 isoform 1, is a member of the nectin family. It is proposed to initiate cell-cell adhesion to promote cell attachment and to allow subsequent formation of JAM- and cadherin-based intercellular junctions. It has been shown to induce endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Subsequent Nectin-3 activity adds strength to the junction through trans-interaction with a variety of molecules. Recombinant human NECTIN3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 39.1kDa (355aa) 40-57kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_056295
- UniProt
- Q9NQS3
- Pathways
- Cell-Cell Junction Organization
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