nectin-3 Protein (His tag)
Quick Overview for nectin-3 Protein (His tag) (ABIN7318809)
Target
See all nectin-3 (NECTIN3) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This nectin-3 protein is labelled with His tag.
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Purpose
- Recombinant Human Nectin-3/PVRL3 Protein (His Tag)
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Sequence
- Gly58-Cys366
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Characteristics
- Recombinant Human Poliovirus Receptor-Related Protein 3 is produced by our Mammalian expression system and the target gene encoding Gly58-Cys366 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) (Active) protein (His-Avi Tag)
NECTIN3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) (Active) protein (Biotin,His-Avi Tag)NECTIN3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) (Active) protein (Fc Tag)NECTIN3 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) (Active) protein (Fc Tag,AVI tag,Biotin)NECTIN3 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Nectin cell adhesion molecule 3 (NECTIN3) (AA 1-366) protein (GST tag)NECTIN3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-404) protein (His tag)NECTIN3 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) protein (His tag)NECTIN3 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Trehalose, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
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Alternative Name
- Nectin-3/PVRL3
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Background
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Background: Nectin-3 is a type I transmembrane glycoprotein that belongs to the nectin family. Its precursor is 549 amino acids in length and contains an extended signal sequence of 57 amino acids, an extracellular domain (ECD) of 347 amino acids, a transmembrane segment of 21 amino acids, and a cytoplasmic region of 124 amino acids. It is predominantly expressed in testis and placenta as well as in various cell lines, including epithelial cell lines. Nectin-3 plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/Nectin-2 at Sertoli-spermatid junctions. Nectin-3 is also involved in the formation of cell-cell junctions, including adherens junctions and synapses.
Synonym: Poliovirus Receptor-Related Protein 3, CDw113, Nectin-3, CD113, PVRL3, PRR3,PVRR3
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Molecular Weight
- 35.0 kDa
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UniProt
- Q9NQS3
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Pathways
- Cell-Cell Junction Organization
Target
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