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DLD Protein (AA 36-509) (His tag)

DLD Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN666962
  • Target See all DLD Proteins
    DLD (Dihydrolipoamide Dehydrogenase (DLD))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 36-509
    Origin
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This DLD protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    DLD, 36-509aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product DLD Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 0.1M NaCl, 10% glycerol
    Storage
    4 °C
  • Target
    DLD (Dihydrolipoamide Dehydrogenase (DLD))
    Alternative Name
    DLD (DLD Products)
    Synonyms
    DLDD Protein, DLDH Protein, E3 Protein, GCSL Protein, LAD Protein, PHE3 Protein, AI315664 Protein, AI746344 Protein, wu:fb24b05 Protein, DLD Protein, DDBDRAFT_0183800 Protein, DDBDRAFT_0216232 Protein, DDB_0183800 Protein, DDB_0216232 Protein, sc:d0402 Protein, dihydrolipoamide dehydrogenase Protein, dihydrolipoyl dehydrogenase Protein, deltaD Protein, DLD Protein, Dld Protein, dldh Protein, AT4G16155 Protein, CND05840 Protein, bfmBC Protein, GCSL Protein, LACBIDRAFT_182385 Protein, UREG_06178 Protein, lpd Protein, TAGG_RS02070 Protein, Arnit_2606 Protein, Mesil_1945 Protein, Trad_2118 Protein, Acear_0640 Protein, Fbal_0372 Protein, Ilyop_1890 Protein, Ftrac_1733 Protein, Ocepr_1753 Protein, Intca_2017 Protein, Deima_0504 Protein, dld Protein
    Background
    DLD (Dihydrolipoamide dehydrogenase), also known as GCSL (glycine cleavage system L protein), is a component of the glycine cleavage system as well as of the alpha ketoacid dehydrogenase complexes. DLD is a flavin-dependent oxidoreductase and functions as a component of the alpha-keto acid dehydrogenase, the pyruvate dehydrogenase, the alpha-ketoglutarate dehydrogenase, the branched-chain alpha-keto acid dehydrogenase and as the L protein in the mitochondrial glycine cleavage system. Mutations in DLD protein can result in MSUD (maple syrup urine disease) and congenital infantile lactic acidosis. Recombinant human DLD protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DLDH, E3, GCSL, LAD, PHE3, Dihydrolipoyl dehydrogenase, mitochondrial Diaphorase, Dihydrolipoamide dehydrogenase, Dihydrolipoyl dehydrogenase, Dihydrolipoyl dehydrogenase mitochondrial, DLD, E3 component of pyruvate dehydrogenase, E3 component of pyruvate dehydrogenase complex 2 oxo glutarate complex branched chain keto acid dehydrogenase complex, Glycine cleavage system L protein, Glycine cleavage system protein L, Lipoamide reductase, Lipoyl dehydrogenase, PHE 3,. NCBI no.: NP_000099
    Molecular Weight
    54.4 kDa (511aa)
    Pathways
    Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis
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