USH1C Protein (AA 1-533) (His tag)

Catalog No. ABIN667114

Recombinant USH1C protein expressed in Escherichia coli (E. coli).

Quick Overview for USH1C Protein (AA 1-533) (His tag) (ABIN667114)

Target: USH1C (Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS - PAGE

Product Details

Protein Characteristics: AA 1-533

Purification tag / Conjugate: This USH1C protein is labelled with His tag.

Characteristics: Harmonin, 1-533aa, Human, His-tagged, Recombinant, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol.

Storage: 4 °C

Target Details

Target: USH1C (Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C))

Alternative Name: Harmonin

Background: Harmonin, product encoded by USH1c gene, is a scaffold protein that functions in the assembly of Usher protein complexes. Usher syndrome type I caused by mutations in USH1C is an autosomal recessive sensory defect involving congenital profound sensorineural deafness, vestibular dysfunction, and blindness due to progressive retinitis pigmentosa. Hormonin has the ability to bind to many other proteins in cell membranes and coordinates their activities. Recombinant human Harmonin protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Harmonin, USH1C, AIE-75, DFNB18, NY-CO-37, NY-CO-38, PDZ-45, PDZ-73, PDZ-73/NY-CO-38, AIE 75, AIE75, Antigen NY CO 38/NY CO 37, Autoimmune enteropathy related antigen AIE 75, Autoimmune enteropathy related antigen AIE75, Deafness autosomal recessive 18, DFNB 18, NY CO 37, NY CO 38, PDZ 45, PDZ 73, PDZ 73 protein, PDZ 73/NY CO 38, PDZ45, PDZ73, PDZ73 protein, Renal carcinoma antigen NY REN 3, USH 1C, Ush1cpst, Usher syndrome 1C, Usher syndrome type 1C protein, Usher syndrome 1C (autosomal recessive severe). NCBI no.: AAH16057

Molecular Weight: 64.6 kDa (570aa)

Pathways: Sensory Perception of Sound