PPCDC Protein (AA 1-204) (His tag)
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- Target See all PPCDC Proteins
- PPCDC (phosphopantothenoylcysteine Decarboxylase (PPCDC))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-204
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PPCDC protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PPCDC, 1-204aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS – PAGE
- Top Product
- Discover our top product PPCDC Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
- Storage
- 4 °C
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- Target
- PPCDC (phosphopantothenoylcysteine Decarboxylase (PPCDC))
- Alternative Name
- PPCDC (PPCDC Products)
- Synonyms
- MDS018 Protein, 1810057I13Rik Protein, 8430432M10Rik Protein, RGD1306267 Protein, phosphopantothenoylcysteine decarboxylase Protein, PPCDC Protein, Ppcdc Protein
- Background
- PPCDC belongs to the HFCD (homo oligomeric flavin containing Cys decarboxylase) superfamily that plays a role in the biosynthesis of coenzyme A (CoA) from pantothenate (Vitamin B). The biosynthesis of CoA from pantothenate requires several steps: the phosphorylation of pantothenate, the conversion of 4’-hosphopantothenate to 4'-phosphopantetheine, the adenylation by phosphopantetheine adenylyltransferase to form dephospho-CoA and the phosphorylation by dephospho-CoA kinase to form CoA. PPCDC plays a direct role in this pathway by converting 4'-phosphopantothenate into 4'-phosphopantetheine. Recombinant human PPCDC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Phosphopantothenoylcysteine decarboxylase, MDS018, PPC-DC, COAC, FLJ14585. NCBI no.: AAH14409
- Molecular Weight
- 24.6 kDa (224aa), confirmed by MALDI-TOF
- Pathways
- Ribonucleoside Biosynthetic Process
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