NUDT3 Protein (AA 1-172) (His tag)
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- Target See all NUDT3 Proteins
- NUDT3 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 3 (NUDT3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-172
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NUDT3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- NUDT3, 1-172aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product NUDT3 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol
- Storage
- 4 °C
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- Target
- NUDT3 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 3 (NUDT3))
- Alternative Name
- NUDT3 (NUDT3 Products)
- Synonyms
- DIPP Protein, DIPP-1 Protein, DIPP1 Protein, 1110011B09Rik Protein, AA960325 Protein, Dipp Protein, NUDT3 Protein, zgc:55746 Protein, zgc:103443 Protein, nudix hydrolase 3 Protein, nudix (nucleotide diphosphate linked moiety X)-type motif 3 Protein, nudix (nucleoside diphosphate linked moiety X)-type motif 3a Protein, nudix (nucleoside diphosphate linked moiety X)-type motif 3b Protein, NUDT3 Protein, Nudt3 Protein, nudt3a Protein, nudt3b Protein
- Background
- NUDT3, also known as DIPP, DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1), is a 172 amino acid cytoplasmic protein belonging to the nudix hydrolase family and DIPP subfamily. NUDT3 acts as a negative regulator of the ERK 1/2 pathway and hydrolyzes 5-phosphoribose 1-diphosphate. NUDT3 exists as a monomer and binds magnesium as a cofactor. Also NUDT3 is widely expressed but found at highest levels in liver, pancreas, brain and heart. Recombinant human NUDT3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Nudix (nucleoside diphosphate linked moiety X)-type motif 3, DIPP, DIPP1. NCBI no.: NP_006694
- Molecular Weight
- 21.6 kDa (192aa), confirmed by MALDI-TOF
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