NUDT21 Protein (AA 1-227) (His tag)

Catalog No. ABIN667366

Product Details

Target: NUDT21 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 21 (NUDT21))

Protein Type: Recombinant

Protein Characteristics: AA 1-227

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NUDT21 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: NUDT21, 1-227aa, Human, His tag, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 2mM DTT, 20% glycerol

Storage: 4 °C

Target Details

Target: NUDT21 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 21 (NUDT21))

Alternative Name: NUDT21 (NUDT21 Products)

Synonyms: CFIM25 Protein, CPSF5 Protein, 25kDa Protein, 3110048P04Rik Protein, 5730530J16Rik Protein, AU014860 Protein, AW549947 Protein, Cpsf5 Protein, zgc:63966 Protein, cpsf5 Protein, An16g01870 Protein, AO090003001316 Protein, Afu5g02030 Protein, T9L24.30 Protein, T9L24_30 Protein, atnudt21 Protein, nudix hydrolase homolog 21 Protein, nudix hydrolase 21 Protein, nudix (nucleoside diphosphate linked moiety X)-type motif 21 Protein, nudix hydrolase 21 L homeolog Protein, cleavage and polyadenylation specificity factor subunit 5 Protein, cleavage and polyadenylation specific factor 5 Protein, autocrine motility factor receptor Protein, nudix hydrolase homolog 21 Protein, NUDT21 Protein, Nudt21 Protein, nudt21 Protein, nudt21.L Protein, ANI_1_1518144 Protein, AOR_1_2312154 Protein, PTRG_11035 Protein, PAAG_04662 Protein, MCYG_02022 Protein, VDBG_06706 Protein, MGYG_04057 Protein, cpsf5 Protein, PGTG_05353 Protein, Tsp_03672 Protein, LOC732888 Protein, AFUA_5G02030 Protein, NFIA_040090 Protein, ACLA_003240 Protein, CC1G_07993 Protein, PMAA_039710 Protein, AFLA_025180 Protein, TSTA_079060 Protein, BDBG_01565 Protein, TERG_04393 Protein

Background: NUDT21, also known as CPSF5 or CFIm25, is a member of the Nudix hydrolase family of pyrophosphatases. This protein localizes to the paraspeckles and forms a heterodimer with CPSF6 or CPSF7 to comprise the CFIm (mammalian cleavage factor I) complex. NUDT21 is the smaller subunit of the complex and is present in all heterodimer combinations. NUDT21 plays an important role in pre-mRNA 3' cleavage and polyadenylation processing. Recombinant human NUDT21 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Nudix (nucleoside diphosphate linked moiety X)-type motif 21, CFIM25, CPSF5, DKFZp686H1588. NCBI no.: NP_008937

Molecular Weight: 28.3 kDa (247aa), confirmed by MALDI-TOF