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NDE1 Protein (NDE1) (AA 1-335) (His tag)

NDE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN667430
  • Target See all NDE1 Proteins
    NDE1
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-335
    Origin
    • 5
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This NDE1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    NDE1, 1-335aa, Human, His tag, E.coli
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product NDE1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol, 5mM DTT, 0.2M NaCl.
    Storage
    4 °C
  • Target
    NDE1
    Alternative Name
    NDE1 (NDE1 Products)
    Synonyms
    2810027M15Rik Protein, AU042936 Protein, AW822251 Protein, Nude Protein, mNudE Protein, HOM-TES-87 Protein, LIS4 Protein, NDE Protein, NUDE Protein, NUDE1 Protein, fb82g01 Protein, im:7141877 Protein, wu:fb82g01 Protein, zgc:114109 Protein, nudE neurodevelopment protein 1 Protein, Nde1 Protein, NDE1 Protein, nde1 Protein
    Background
    NDE1 is a cytoplasmic protein belonging to the nudE protein family. Phosphorylated during mitosis, it is essential for the formation and function of the mitotic spindle in M phase and functions to regulate the Dynein-mediated transport of kinetochore proteins, as well as centrosome duplication during interphase. NDE1 is thought to interact with NDEL1, LIS1 and Dynein IC1/2, cytosolic in a signaling pathway that regulates the formation of neurons and is fundamental to the development of the cerebral cortex. Recombinant human NDE1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Nuclear distribution protein nudE homolog 1, FLJ20101, HOM-TES-87, NUDE, NUDE, nudE nuclear distribution gene E homolog 1 (A. nidulans). NCBI no.: NP_001137451
    Molecular Weight
    39.9 kDa (355aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
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