NDE1 Protein (NDE1) (AA 1-335) (His tag)
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- Target See all NDE1 Proteins
- NDE1
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-335
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NDE1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- NDE1, 1-335aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product NDE1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol, 5mM DTT, 0.2M NaCl.
- Storage
- 4 °C
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- Target
- NDE1
- Alternative Name
- NDE1 (NDE1 Products)
- Synonyms
- 2810027M15Rik Protein, AU042936 Protein, AW822251 Protein, Nude Protein, mNudE Protein, HOM-TES-87 Protein, LIS4 Protein, NDE Protein, NUDE Protein, NUDE1 Protein, fb82g01 Protein, im:7141877 Protein, wu:fb82g01 Protein, zgc:114109 Protein, nudE neurodevelopment protein 1 Protein, Nde1 Protein, NDE1 Protein, nde1 Protein
- Background
- NDE1 is a cytoplasmic protein belonging to the nudE protein family. Phosphorylated during mitosis, it is essential for the formation and function of the mitotic spindle in M phase and functions to regulate the Dynein-mediated transport of kinetochore proteins, as well as centrosome duplication during interphase. NDE1 is thought to interact with NDEL1, LIS1 and Dynein IC1/2, cytosolic in a signaling pathway that regulates the formation of neurons and is fundamental to the development of the cerebral cortex. Recombinant human NDE1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Nuclear distribution protein nudE homolog 1, FLJ20101, HOM-TES-87, NUDE, NUDE, nudE nuclear distribution gene E homolog 1 (A. nidulans). NCBI no.: NP_001137451
- Molecular Weight
- 39.9 kDa (355aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
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