SUFUH Protein (AA 1-484) (His tag)
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- Target See all SUFUH Proteins
- SUFUH (Suppressor of Fused Homolog (SUFUH))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-484
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SUFUH protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SUFU, 1-484aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SUFUH Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 50mM NaCl
- Storage
- 4 °C
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- Target
- SUFUH (Suppressor of Fused Homolog (SUFUH))
- Alternative Name
- SUFU (SUFUH Products)
- Synonyms
- CG6054 Protein, Dmel\\CG6054 Protein, SU(FU) Protein, SUFU Protein, Su(Fu) Protein, SuFu Protein, Sufu Protein, su(fu) Protein, sufu Protein, Xsufu Protein, sufuh Protein, sufuxl Protein, PRO1280 Protein, SUFUH Protein, SUFUXL Protein, Su(fu) Protein, dre Protein, fi39e05 Protein, wu:fi39e05 Protein, 2810026F04Rik Protein, b2b273Clo Protein, Suppressor of fused Protein, SUFU negative regulator of hedgehog signaling L homeolog Protein, SUFU negative regulator of hedgehog signaling Protein, suppressor of fused homolog (Drosophila) Protein, Su(fu) Protein, sufu.L Protein, SUFU Protein, sufu Protein, Sufu Protein
- Background
- SUFU (Suppressor of fused homolog) belongs to the SUFU family. This protein is negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. SUFU has been shown to interact with GLI1, GLI3 and PEX26. Recombinant human SUFU protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: suppressor of fused homolog, PRO1280, SUFUH, SUFUXL. NCBI no.: NP_057253
- Molecular Weight
- 56.1kDa (504aa)
- Pathways
- Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
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