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COMMD1 Protein (AA 1-190) (His tag)

COMMD1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667798
  • Target See all COMMD1 Proteins
    COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-190
    Origin
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This COMMD1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    COMMD1, 1-190aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product COMMD1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl
    Storage
    4 °C
  • Target
    COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))
    Alternative Name
    COMMD1 (COMMD1 Products)
    Synonyms
    C2orf5 Protein, MURR1 Protein, murr1 Protein, commd1 Protein, si:ch211-213b8.2 Protein, DDBDRAFT_0184206 Protein, DDBDRAFT_0266452 Protein, DDB_0184206 Protein, DDB_0266452 Protein, COMMD1 Protein, MGC114682 Protein, AI256843 Protein, Murr1 Protein, U2/Mu Protein, copper metabolism domain containing 1 Protein, copper metabolism (Murr1) domain containing 1 Protein, COMM domain-containing protein 1 Protein, copper metabolism domain containing 1 L homeolog Protein, COMM domain containing 1 Protein, COMMD1 Protein, commd1 Protein, comd1 Protein, Commd1 Protein, commd1.L Protein
    Background
    COMMD1, also known as copper metabolism MURR1 domain-containing protein 1, is a 190 amino acid protein responsible for inhibition of TNF-induced NFkB p50 and has a suggested role in facilitation of biliary copper excretion within hepatocytes. High expression is found in liver tissue, with lower expressions in lung, heart, kidney and brain tissue. This protein interacts directly with COMMD6 and ATP7B, and indirectly with IkB-beta and COMMD7. Recombinant human COMMD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: C2orf5, MURR1, COMM domain-containing protein 1, COMMD-1, COMMD 1, COMM, MURR 1, MURR-1. NCBI no.: NP_689729
    Molecular Weight
    23.3 kDa (210aa), confirmed by MALDI-TOF
    Pathways
    Transition Metal Ion Homeostasis
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