Thymidine Phosphorylase Protein (TYMP) (AA 11-482) (His tag)
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- Target See all Thymidine Phosphorylase (TYMP) Proteins
- Thymidine Phosphorylase (TYMP)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 11-482
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Thymidine Phosphorylase protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- TYMP, 11-482aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TYMP Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
- Storage
- 4 °C
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- Target
- Thymidine Phosphorylase (TYMP)
- Alternative Name
- TYMP (TYMP Products)
- Synonyms
- ECGF Protein, ECGF1 Protein, MEDPS1 Protein, MNGIE Protein, MTDPS1 Protein, PDECGF Protein, TP Protein, hPD-ECGF Protein, 2900072D10Rik Protein, Ecgf1 Protein, PD-ECGF Protein, Pdgfec Protein, typh Protein, thymidine phosphorylase Protein, thymidine phosphorylase DeoA Protein, AMP phosphorylase Protein, Thymidine phosphorylase Protein, TYMP Protein, Tymp Protein, deoA Protein, Dd586_0614 Protein, Kvar_4413 Protein, NMAG_RS19330 Protein, Snov_1187 Protein, Fbal_2856 Protein, Ftrac_2071 Protein, Intca_1216 Protein, ARCVE_RS10415 Protein, Sphch_4174 Protein, Sinme_3461 Protein, METOK_RS06355 Protein, Mesop_1831 Protein, typh Protein
- Background
- Thymidine phosphorylase precursor, also known TYMP, is a platelet-derived endothelial cell growth factor that catalyzes the formation of thymine and 2-deoxy-D-ribose-1-phosphate from thymidine and orthophosphate. It is an angiogenic inducer that potently stimulates the growth of endothelial cells and induces chemotaxis. Increased expression of TYMP is seen in a wide variety of different solid tumors and inflammatory diseases and is often associated with poor prognosis. Recombinant human TYMP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ECGF1, hPD-ECGF, MNGIE, PDECGF, TP, Gliostatin, Thymidine phosphorylase. NCBI no.: NP_001107228
- Molecular Weight
- 51.3 kDa (493aa), confirmed by MALDI-TOF
- Pathways
- Signaling Events mediated by VEGFR1 and VEGFR2
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