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CD70 Protein (mFc-His Tag)

Recombinant CD70 protein expressed in HEK-293 Cells.
Catalog No. ABIN6961112

Quick Overview for CD70 Protein (mFc-His Tag) (ABIN6961112)

Target

See all CD70 Proteins
CD70 (CD70 Molecule (CD70))

Protein Type

Recombinant

Origin

  • 31
  • 9
  • 1
  • 1
  • 1
Human

Source

  • 26
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Application

ELISA

Purity

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Purification tag / Conjugate

    This CD70 protein is labelled with mFc-His Tag.

    Purpose

    Recombinant human CD70 protein with N-terminal mouse Fc and C-terminal 6xHis tag

    Specificity

    MFc (Pro99-Lys330) CD70 (Gln39-Pro193) 6xHis

    Characteristics

    Extracellular Domain Protein

    Purification

    Purified from cell culture supernatant by affinity chromatography
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    Product
    Expression System
    Conjugate
    Origin
    Price starts at
    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $16,231.82
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    CD70 (CD70 Molecule (CD70))

    Alternative Name

    CD70

    Background

    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

    Molecular Weight

    predicted molecular mass of 45.6 kDa after removal of the signal peptide.

    Gene ID

    970

    UniProt

    P32970

    Pathways

    Cancer Immune Checkpoints
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