CD70 Protein (mFc-His Tag)
Quick Overview for CD70 Protein (mFc-His Tag) (ABIN6961112)
Target
See all CD70 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This CD70 protein is labelled with mFc-His Tag.
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Purpose
- Recombinant human CD70 protein with N-terminal mouse Fc and C-terminal 6xHis tag
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Specificity
- MFc (Pro99-Lys330) CD70 (Gln39-Pro193) 6xHis
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- CD70 (CD70 Molecule (CD70))
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Alternative Name
- CD70
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Background
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
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Molecular Weight
- predicted molecular mass of 45.6 kDa after removal of the signal peptide.
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Gene ID
- 970
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UniProt
- P32970
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Pathways
- Cancer Immune Checkpoints
Target
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