Angiopoietin 2 Protein (ANGPT2) (Fc Tag)
Quick Overview for Angiopoietin 2 Protein (ANGPT2) (Fc Tag) (ABIN6964143)
Target
See all Angiopoietin 2 (ANGPT2) ProteinsProtein Type
Origin
Source
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Purification tag / Conjugate
- This Angiopoietin 2 protein is labelled with Fc Tag.
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Sequence
- ANGPT2(Lys275-Phe496)+hFc(Glu99-Ala330)
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Characteristics
- Tagged Protein: C-Human Fc tag
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Purification
- affinity purification
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with deionized water
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Preservative
- Without preservative
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Storage
- -80 °C
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Storage Comment
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
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Expiry Date
- 12 months
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- Angiopoietin 2 (ANGPT2)
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Alternative Name
- ANGPT2
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Background
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Synonymes: ANGPT2,AGPT2,ANG2,Angiopoietin-2
Description: The protein encoded by this gene is an antagonist of angiopoietin 1 (Ang-1), and both (Ang-1 and Ang-2) are ligands for the endothelial tyrosine kinase receptor (Tie2). These two ligands affect angiogenesis during embryogenesis and tumorigenesis. The encoded protein disrupts the vascular remodeling ability of Ang-1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. -
Molecular Weight
- 49.94 kDa
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UniProt
- O15123
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Pathways
- RTK Signaling
Target
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