CD51 Protein (Fc Tag)
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- Target See all CD51 (ITGAV) Proteins
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD51 protein is labelled with Fc Tag.
- Sequence
- ITGAV(Phe31-Val992)+ ITGB1(Gln21-Asp728)+hFc(Glu99-Ala330)
- Characteristics
- Tagged Protein: C-Human Fc tag
- Purification
- affinity purification
- Top Product
- Discover our top product ITGAV Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -80 °C
- Storage Comment
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- Expiry Date
- 12 months
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- Target
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- Alternative Name
- ITGAV (ITGAV Products)
- Synonyms
- 1110004F14Rik Protein, 2610028E01Rik Protein, CD51 Protein, D430040G12Rik Protein, MSK8 Protein, VNRA Protein, VTNR Protein, Cd51 Protein, integrin subunit alpha V Protein, integrin alpha V Protein, ITGAV Protein, Itgav Protein
- Background
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Synonymes: CD51, MSK8, VNRA, VTNR
Description: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. - Molecular Weight
- 131.34 kDa
- UniProt
- P06756
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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