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CD51 Protein (Fc Tag)

ITGAV Origin: Human Host: HEK-293 Cells Recombinant
Catalog No. ABIN6964181
  • Target See all CD51 (ITGAV) Proteins
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Protein Type
    Recombinant
    Origin
    • 8
    • 5
    • 1
    Human
    Source
    • 8
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD51 protein is labelled with Fc Tag.
    Sequence
    ITGAV(Phe31-Val992)+ ITGB1(Gln21-Asp728)+hFc(Glu99-Ala330)
    Characteristics
    Tagged Protein: C-Human Fc tag
    Purification
    affinity purification
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    Discover our top product ITGAV Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Preservative
    Without preservative
    Storage
    -80 °C
    Storage Comment
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Expiry Date
    12 months
  • Target
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Alternative Name
    ITGAV (ITGAV Products)
    Synonyms
    1110004F14Rik Protein, 2610028E01Rik Protein, CD51 Protein, D430040G12Rik Protein, MSK8 Protein, VNRA Protein, VTNR Protein, Cd51 Protein, integrin subunit alpha V Protein, integrin alpha V Protein, ITGAV Protein, Itgav Protein
    Background
    Synonymes: CD51, MSK8, VNRA, VTNR
    Description: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
    Molecular Weight
    131.34 kDa
    UniProt
    P06756
    Pathways
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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