CCR2 Protein (Fc Tag)
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- Target See all CCR2 Proteins
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCR2 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CCR2 with C-terminal human Fc tag
- Specificity
- CCR2 (Met1-Ala42) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CCR2 Protein
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Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-360) (Active) protein-VLP
CCR2 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, Func, SPR Active
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-360) (Active) protein-VLP (Biotin)CCR2 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, Func, SPR Active
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-42) protein (GST tag)CCR2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-374) protein (Strep Tag)Crystallography grade CCR2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-373) protein (Strep Tag)Crystallography grade CCR2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
- Alternative Name
- CCR2 (CCR2 Products)
- Synonyms
- CC-CKR-2 Protein, CCR-2 Protein, CCR2A Protein, CCR2B Protein, CD192 Protein, CKR2 Protein, CKR2A Protein, CKR2B Protein, CMKBR2 Protein, MCP-1-R Protein, ACKR5 Protein, CKRX Protein, CRAM Protein, CRAM-A Protein, CRAM-B Protein, HCR Protein, Cc-ckr-2 Protein, Ccr2a Protein, Ccr2b Protein, Ckr2 Protein, Ckr2a Protein, Ckr2b Protein, Cmkbr2 Protein, mJe-r Protein, C-C motif chemokine receptor 2 Protein, C-C motif chemokine receptor like 2 Protein, chemokine (C-C motif) receptor 2 Protein, CCR2 Protein, CCRL2 Protein, Ccr2 Protein, LOC484790 Protein
- Background
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Synonymes: CC-CKR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R
Description: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq] - Molecular Weight
- predicted molecular mass of 31.0 kDa after removal of the signal peptide.The apparent molecular mass of CCR2-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P41597
- Pathways
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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