MMP11 Protein (Fc Tag)

Catalog No. ABIN6964295

Product Details

Target: MMP11 (Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This MMP11 protein is labelled with Fc Tag.

Purpose: Recombinant human MMP11 protein with C-terminal human Fc tag

Specificity: MMP11 (Arg32-Leu488) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: affinity purification

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Preservative: Without preservative

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: MMP11 (Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))

Alternative Name: MMP11 (MMP11 Products)

Synonyms: SL-3 Protein, ST3 Protein, STMY3 Protein, Stmy3 Protein, MMP-11 Protein, matrix metallopeptidase 11 Protein, matrix metallopeptidase 11 L homeolog Protein, stromelysin-3 Protein, MMP11 Protein, Mmp11 Protein, mmp11.L Protein, LOC103694874 Protein

Background: Synonymes: SL-3, ST3, STMY3
Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]

Molecular Weight: predicted molecular mass of 76.5 kDa after removal of the signal peptide.The apparent molecular mass of MMP11-hFc is 70-100 kDa due to glycosylation.

UniProt: P24347