CCR3 Protein (Fc Tag)
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- Target See all CCR3 Proteins
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCR3 protein is labelled with Fc Tag.
- Purpose
- Recombinant human CCR3 protein with C-terminal human Fc tag
- Specificity
- CCR3 (Met1-Ala34) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CCR3 Protein
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Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 1-355) protein (GST tag)
CCR3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 1-355) protein (Strep Tag)Crystallography grade CCR3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 1-359) protein (Strep Tag)Crystallography grade CCR3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
- Alternative Name
- CCR3 (CCR3 Products)
- Synonyms
- CC-CKR-3 Protein, CD193 Protein, CKR3 Protein, CMKBR3 Protein, CC-CKR3 Protein, Cmkbr1l2 Protein, Cmkbr3 Protein, C-C motif chemokine receptor 3 Protein, chemokine (C-C motif) receptor 3 Protein, CCR3 Protein, Ccr3 Protein
- Background
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Synonymes: CC-CKR-3, CD193, CKR3, CMKBR3
Description: The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009] - Molecular Weight
- predicted molecular mass of 29.9 kDa after removal of the signal peptide. The apparent molecular mass of CCR3-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P51677
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