SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) (Active) protein (His tag)
SARS-CoV N
Origin: SARS Coronavirus (SARS-CoV)
Host: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
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- Target See all SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N) Proteins
- SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- SARS Coronavirus (SARS-CoV)
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- His tag
- Sequence
- AA 1-422
- Characteristics
- SARS Nucleocapsid protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 422 (Accession # NP_828858.1).
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, Arginine, pH 7.4,
- Storage
- -20 °C
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- Target
- SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N)
- Alternative Name
- SARS Nucleocapsid protein (SARS-CoV N Products)
- Synonyms
- NC Protein, Protein N Protein, nucleocapsid protein Protein, N Protein
- Target Type
- Viral Protein
- Background
- Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology, 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
- Molecular Weight
- 47.7 kDa
- NCBI Accession
- NP_828858
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