CD3G Protein (AA 23-116) (Fc Tag)
-
- Target See all CD3G Proteins
- CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-116
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD3G protein is labelled with Fc Tag.
- Characteristics
- Human CD3 gamma / CD3G Protein, Fc Tag (MALS verified)
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CD3G Protein
-
CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-111) protein (GST tag)
CD3G Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-182) protein (rho-1D4 tag)Crystallography grade CD3G Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-182) protein (rho-1D4 tag)Crystallography grade CD3G Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-116) protein (His tag)CD3G Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE SDS
-
- Application Notes
- MALS verified
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
-
- Target
- CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))
- Alternative Name
- CD3 gamma (CD3G Products)
- Synonyms
- Ctg-3 Protein, Ctg3 Protein, T3g Protein, CD3-GAMMA Protein, T3G Protein, CD3 antigen, gamma polypeptide Protein, CD3g molecule Protein, Cd3g Protein, CD3G Protein
- Background
- CD3 gamma chain is part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. In addition to this role of signal transduction in T-cell activation, CD3G plays an essential role in the dynamic regulation of TCR expression at the cell surface. Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G.
- Molecular Weight
- 37.1 kDa
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events
-
