Secretory Component Protein (AA 19-603) (Twin-Strep tag)
Origin: Human
Host: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
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- Target See all Secretory Component products
- Secretory Component
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-603
- Origin
- Human
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Secretory Component protein is labelled with Twin-Strep tag.
- Purpose
- Human Secretory Component, Twin Strep Tag
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.3
- Storage
- -20 °C
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- Target
- Secretory Component
- Abstract
- Secretory Component Products
- Synonyms
- RNPIGR2 Protein, pIgA-R Protein, polymeric immunoglobulin receptor Protein, PIGR Protein, Pigr Protein
- Background
- The secretory component (SC) is a unique polypeptide chain that may be found in immunoglobulins A and M (IgA and IgM). The SC wraps around two IgA units joined by a J chain protein fragment, resulting in a configuration with each of the two antigen binding regions of the two constituent y-shaped antibodies exposed. One identified function of secretory components is to protect IgA antibodies from degradation by the gastric acids and enzymes of the digestive system. It also appears that SC may serve in the three-dimensional organization or in the transport and distribution of the resulting IgA complexes.
- Molecular Weight
- 67.6 kDa
- NCBI Accession
- NP_002635
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