MERS-Coronavirus Spike Protein (AA 18-751) (His tag)
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- Target See all MERS-Coronavirus Spike (MERS-CoV S) products
- MERS-Coronavirus Spike (MERS-CoV S) (MERS-Coronavirus Spike Protein (MERS-CoV S))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 18-751
- Origin
- Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MERS-Coronavirus Spike protein is labelled with His tag.
- Characteristics
- MERS S1 protein, His Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- MERS-Coronavirus Spike (MERS-CoV S) (MERS-Coronavirus Spike Protein (MERS-CoV S))
- Alternative Name
- MERS S1 protein (MERS-CoV S Products)
- Target Type
- Viral Protein
- Background
- It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
- Molecular Weight
- 83.1 kDa
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