SARS-CoV-2 Spike Protein (His tag)

Catalog No. ABIN7013277

This Recombinant SARS-CoV-2 Spike protein is expressed in HEK-293 Cells.

Quick Overview for SARS-CoV-2 Spike Protein (His tag) (ABIN7013277)

Target: SARS-CoV-2 Spike

Protein Type: Recombinant

Biological Activity: Active

Origin: SARS Coronavirus-2 (SARS-CoV-2)

Source: HEK-293 Cells

Purity: >95 % as determined by SDS-PAGE.

Product Details

Purification tag / Conjugate: This SARS-CoV-2 Spike protein is labelled with His tag.

Sequence: AA 16-1213

Specificity: SARS-CoV-2 S protein (F817P, A892P, A899P, A942P, K986P, V987P), His Tag (MALS verified)

Characteristics: SARS-CoV-2 S protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Application Notes: MALS verified

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS

Storage: -20 °C

Target Details

Target: SARS-CoV-2 Spike

Alternative Name: SARS-CoV-2 S protein

Target Type: Viral Protein

Background: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Molecular Weight: 138.2 kDa