SLC39A6 Protein (AA 29-325) (His tag,AVI tag,Biotin)

Catalog No. ABIN7013486

Product Details

Target: SLC39A6 (Solute Carrier Family 39 (Zinc Transporter), Member 6 (SLC39A6))

Protein Type: Recombinant

Biological Activity: Active

Protein Characteristics: AA 29-325

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SLC39A6 protein is labelled with His tag,AVI tag,Biotin.

Purpose: Biotinylated Human LIV-1 / SLC39A6 Protein, His,Avitag™

Specificity: Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

Purity: >90 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Comment:

Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: SLC39A6 (Solute Carrier Family 39 (Zinc Transporter), Member 6 (SLC39A6))

Alternative Name: LIV-1 (SLC39A6 Products)

Synonyms: liv1 Protein, wu:fc25a09 Protein, ZIP6 Protein, Ermelin Protein, LIV-1 Protein, solute carrier family 39 (zinc transporter), member 6 Protein, solute carrier family 39 member 6 Protein, solute carrier family 39 (metal ion transporter), member 6 Protein, slc39a6 Protein, SLC39A6 Protein, Slc39a6 Protein

Background: LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.

Molecular Weight: 37.2 kDa

Pathways: Transition Metal Ion Homeostasis