Sialoadhesin/CD169 Protein (AA 20-1641) (His tag)
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- Target See all Sialoadhesin/CD169 (SIGLEC1) Proteins
- Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-1641
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Sialoadhesin/CD169 protein is labelled with His tag.
- Sequence
- AA 20-1641
- Characteristics
- Cynomolgus Siglec-10 Protein, His Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SIGLEC1 Protein
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Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) (AA 20-1639) protein (His tag)
Crystallography grade SIGLEC1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) protein (Myc-DYKDDDDK Tag)SIGLEC1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- MES,NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
- Alternative Name
- Siglec-1 (SIGLEC1 Products)
- Synonyms
- Cd169 Protein, Siglec-1 Protein, Sn Protein, CD169 Protein, SIGLEC-1 Protein, SN Protein, dJ1009E24.1 Protein, SA Protein, SIGLEC1 Protein, p210 Protein, pSn Protein, sialic acid binding Ig like lectin 1 Protein, sialic acid binding Ig-like lectin 1, sialoadhesin Protein, SIGLEC1 Protein, Siglec1 Protein
- Background
- Alternate names for sialoadhesin include siglec-1 and CD169 (cluster of differentiation 169). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. It is defined as an I-type lectin, since it contains 17 immunoglobulin (Ig) domains (one variable domain and 16 constant domains), and thus also belongs to the immunoglobulin superfamily (IgSF). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells.
- Molecular Weight
- 175.1 kDa
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