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SLC7A11 Protein (Fc Tag)

SLC7A11 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7092733
  • Target See all SLC7A11 Proteins
    SLC7A11 (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    • 2
    Human
    Source
    • 4
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SLC7A11 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human SLC7A11 Protein with C-terminal human Fc tag
    Specificity
    SLC7A11 (Lys67-Gly74) (Leu151-Cys158) (Lys215-Thr233) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product SLC7A11 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    SLC7A11 (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))
    Alternative Name
    SLC7A11 (SLC7A11 Products)
    Synonyms
    SLC7A11 Protein, DKFZp468E122 Protein, CCBR1 Protein, xCT Protein, 9930009M05Rik Protein, AI451155 Protein, sut Protein, solute carrier family 7 member 11 Protein, solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 Protein, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Protein, SLC7A11 Protein, Slc7a11 Protein
    Background
    Synonymes: CCBR1, xCT
    Description: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
    Molecular Weight
    predicted molecular mass of 33.4 kDa after removal of the signal peptide.The apparent molecular mass of SLC7A11-hFc is 35-55 kDa due to glycosylation.
    UniProt
    Q9UPY5
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