HSV2 gD Protein (His tag)

Catalog No. ABIN7121363

Product Details

Target: HSV2 gD (Herpes Simplex Virus Type 2, Glycoprotein D (HSV2 gD))

Protein Type: Recombinant

Origin: Herpes simplex virus type 2

Source: HEK-293 Cells

Purification tag / Conjugate: This HSV2 gD protein is labelled with His tag.

Purpose: HSV-2 (strain HG52) Envelope Glycoprotein D (gD), His Tag (MALS verified)

Sequence: Lys 26 - Tyr 310

Characteristics: HSV-2 (strain HG52) Envelope Glycoprotein D (gD), His Tag (GLD-V52H4) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Tyr 310 (Accession # P03172-1).

Purity: >95 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Grade: MALS verified

Application Details

Application Notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 33.7 kDa. The protein migrates as 44-47 kDa under reducing (R) condition due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: HSV2 gD (Herpes Simplex Virus Type 2, Glycoprotein D (HSV2 gD))

Alternative Name: HSV-2 (strain HG52) Envelope Glycoprotein D (gD) (HSV2 gD Products)

Background: Synonyms: gD,
Description: Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. Glycoprotein D (gD) is a structural component of the herpes simplex virus type 1 (HSV-1) envelope which is essential for virus entry and fusion with host cells. gD plays an important role by binding to the host receptors such as herpes virus entry mediator (HVEM) and nectin-1, a member of the immunoglobulin (Ig)-like cell adhesion molecules.

Molecular Weight: 33.7 kDa