ABHD4 Protein (His tag)
-
- Target See all ABHD4 Proteins
- ABHD4 (Abhydrolase Domain Containing 4 (ABHD4))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This ABHD4 protein is labelled with His tag.
- Purpose
- Recombinant Human ABHD4 Protein (His Tag)
- Sequence
- Met 1-Asp 342
- Characteristics
- A DNA sequence encoding the full length of human ABHD4 (NP_071343.2) (Met 1-Asp 342) was expressed, with a polyhistidine tag at the N-terminus.
- Purity
- > 82 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ABHD4 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- ABHD4 (Abhydrolase Domain Containing 4 (ABHD4))
- Alternative Name
- ABHD4 (ABHD4 Products)
- Synonyms
- ABH4 Protein, abhd5 Protein, 1110035H23Rik Protein, AI429574 Protein, Abh4 Protein, ABHD4 Protein, zgc:110267 Protein, abhydrolase domain containing 4 Protein, ABHD4 Protein, abhd4 Protein, Abhd4 Protein
- Background
-
Background: Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipase B that selectively hydrolyzes N-acyl phosphatidylethanolamines (NAPEs) and lysoNAPEs. ABH4 accepts lysoNAPEs bearing both saturated and polyunsaturated N-acyl chains as substrates and displays a distribution that closely mirrors lysoNAPE-lipase activity in mouse tissues. The existence of an NAPE-PLD-independent route for NAE biosynthesis and suggest that ABH4 plays a role in this metabolic pathway by acting as a (lyso)NAPE-selective lipase.
Synonym: ABH4
- Molecular Weight
- 41 kDa
- NCBI Accession
- NP_071343
-