Adenylate Kinase 2 Protein (AK2) (GST tag,His tag)
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- Target See all Adenylate Kinase 2 (AK2) Proteins
- Adenylate Kinase 2 (AK2)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This Adenylate Kinase 2 protein is labelled with GST tag,His tag.
- Purpose
- Recombinant Human AK2/Adenylate kinase 2 Protein (His & GST Tag)
- Sequence
- Met 1-Ile 239
- Characteristics
- A DNA sequence encoding the human AK2 isoform 1 (P54819-1) (Met 1-Ile 239) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product AK2 Protein
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Adenylate Kinase 2 (AK2) (AA 1-239) protein (His tag)
AK2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Adenylate Kinase 2 (AK2) (AA 1-239) protein (His tag)AK2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Adenylate Kinase 2 (AK2) (AA 1-239) protein (GST tag)AK2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Adenylate Kinase 2 (AK2) (AA 1-96) protein (GST tag)AK2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Adenylate Kinase 2 (AK2) (AA 1-239) protein (Strep Tag)Crystallography grade AK2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Adenylate Kinase 2 (AK2) (AA 2-239) protein (His tag)Crystallography grade AK2 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Adenylate Kinase 2 (AK2) (AA 2-239) protein (His tag)Crystallography grade AK2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol, 3 mM DTT
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- Adenylate Kinase 2 (AK2)
- Alternative Name
- AK2/Adenylate kinase 2 (AK2 Products)
- Synonyms
- ADK-2 Protein, BcDNA:SD09634 Protein, CG3140 Protein, Dak2 Protein, Dmel\\CG3140 Protein, anon-Dak2 Protein, adk2 Protein, NV10896 Protein, wu:fb34f05 Protein, wu:fj80e03 Protein, ADK2 Protein, AK 2 Protein, Ak-2 Protein, D4Ertd220e Protein, MXI22.8 Protein, MXI22_8 Protein, Adenylate kinase 2 Protein, adenylate kinase 2 Protein, adenylate kinase Protein, adenylate kinase 2 S homeolog Protein, Adenylate kinase family protein Protein, Adk2 Protein, AK2 Protein, ak2 Protein, LOC100123971 Protein, ak2.S Protein, Ak2 Protein, AT5G50370 Protein
- Background
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Background: Adenylate kinase 2 (AK2) belongs to the Adenylate kinase family that contains three isozymes: AK1, AK2 and AK3. Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Adenylate kinase2 (AK2) is expressed in mitochondrial intermembrane space. It may play a role in apoptosis. It has been demonstrated that in apoptotic cells AK2 was translocated into the cytosol concomitantly with cytochronme C. Mutations in this gene are the cause of reticular dysgenesis. These mutations result in absent or strongly decreased protein expression. It has been also established that AK2 is specifically expressed in the stria vascularis region of the inner ear, which provides an explanation of the sensorineural deafness in these individuals.
Synonym: ADK2;AK2
- Molecular Weight
- 54.3 kDa
- Pathways
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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