DAO Protein (His tag)
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- Target See all DAO (ABP1) Proteins
- DAO (ABP1) (Amiloride Binding Protein 1 (Amine Oxidase (Copper-Containing)) (ABP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This DAO protein is labelled with His tag.
- Purpose
- Recombinant Human Diamine Oxidase/AOC1 Protein (His Tag)
- Sequence
- Glu20-Val751
- Characteristics
- Recombinant Human Amiloride-binding protein 1 is produced by our Mammalian expression system and the target gene encoding Glu20-Val751 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ABP1 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl,10 % Glycerol, pH 7.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- DAO (ABP1) (Amiloride Binding Protein 1 (Amine Oxidase (Copper-Containing)) (ABP1))
- Alternative Name
- Diamine Oxidase/AOC1 (ABP1 Products)
- Synonyms
- ABP Protein, ABP1 Protein, DAO Protein, DAO1 Protein, KAO Protein, 1600012D06Rik Protein, Abp1 Protein, abp1 Protein, si:ch211-286c5.2 Protein, zgc:154101 Protein, Abp Protein, dao Protein, amine oxidase, copper containing 1 Protein, amine oxidase, copper-containing 1 Protein, AOC1 Protein, Aoc1 Protein, aoc1 Protein
- Background
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Background: Amiloride-sensitive amine oxidase (AOC1) belongs to the copper/topaquinone oxidase family. The protein exists as homodimer by disulfide and mainly located in placenta and kidney. AOC1 catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. The activity of this protein can be inhibited by amiloride in a competitive manner. It is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.
Synonym: Amiloride-sensitive amine oxidase [copper-containing],DAO,Diamine oxidase,Amiloride-binding protein 1,Amine oxidase copper domain-containing protein 1,Histaminase,Kidney amine oxidase,KAO,AOC1,ABP1, DAO1
- Molecular Weight
- 84.4 kDa
- UniProt
- P19801
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