Angiopoietin 1 Protein (ANGPT1) (Fc Tag)

Catalog No. ABIN7319856

This Recombinant Angiopoietin 1 protein is expressed in Human Cells.

Quick Overview for Angiopoietin 1 Protein (ANGPT1) (Fc Tag) (ABIN7319856)

Target: Angiopoietin 1 (ANGPT1)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: >95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This Angiopoietin 1 protein is labelled with Fc Tag.

Purpose: Recombinant Human Angiopoietin-1/ANG1 (N-Fc)

Sequence: Asp256-Phe498

Characteristics: Recombinant Human Angiopoietin-1 is produced by our Mammalian expression system and the target gene encoding Asp256-Phe498 is expressed with a Fc tag at the N-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Angiopoietin 1 (ANGPT1)

Alternative Name: Angiopoietin-1/ANG1

Background:

Background: Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis.

Synonym: AGP1, AGPT, Ang1, ANG-1, angiopoietin 1, Angiopoietin-1, ANGPT1

Molecular Weight: 53.9 kDa

UniProt: Q15389

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process