ATG4A Protein (His tag)
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- Target See all ATG4A Proteins
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ATG4A protein is labelled with His tag.
- Purpose
- Recombinant Human ATG4A Protein (His Tag)
- Sequence
- Met 1-Val398
- Characteristics
- Recombinant Human Autophagy Related 4 Homolog A is produced by our E.coli expression system and the target gene encoding Met1-Val398 is expressed with a 6His tag at the N-terminus.
- Purity
- > 85 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ATG4A Protein
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Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 1-398) protein (His tag)
ATG4A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 1-398) protein (GST tag)ATG4A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 1-398) protein (Strep Tag)Crystallography grade ATG4A Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Autophagy related 4A Cysteine Peptidase (ATG4A) (AA 1-396) protein (Strep Tag)Crystallography grade ATG4A Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
- Alternative Name
- ATG4A (ATG4A Products)
- Synonyms
- apg4a Protein, autl2 Protein, F6E13.27 Protein, APG4A Protein, zgc:111958 Protein, Aut2a Protein, AUTL2 Protein, AI627006 Protein, AV169859 Protein, Apg4a Protein, Atg4al Protein, Autl2 Protein, Atg4a Protein, autophagy related 4A cysteine peptidase L homeolog Protein, autophagy related 4A cysteine peptidase Protein, Peptidase family C54 protein Protein, ATG4 autophagy related 4 homolog A (S. cerevisiae) Protein, autophagy related 4A, cysteine peptidase Protein, atg4a.L Protein, ATG4A Protein, AT2G44140 Protein, atg4a Protein, Atg4a Protein
- Background
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Background: Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy, it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.
Synonym: Cysteine Protease ATG4A, AUT-Like 2 Cysteine Endopeptidase, Autophagin-2, Autophagy-Related Cysteine Endopeptidase 2, Autophagy-Related Protein 4 Homolog A, hAPG4A, ATG4A, APG4A, AUTL2
- Molecular Weight
- 47.5 kDa
- UniProt
- Q8WYN0
- Pathways
- Autophagy
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