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ATG4C Protein (His tag)

ATG4C Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318186
  • Target See all ATG4C Proteins
    ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This ATG4C protein is labelled with His tag.
    Purpose
    Recombinant Human ATG4C Protein (His Tag)
    Sequence
    Met 1-Leu458
    Characteristics
    Recombinant Human Autophagy Related 4 Homolog C is produced by our E.coli expression system and the target gene encoding Met1-Leu458 is expressed with a 6His tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ATG4C Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 10 % Glycerol, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
    Alternative Name
    ATG4C (ATG4C Products)
    Synonyms
    apg4c Protein, atg4cl Protein, zgc:86888 Protein, wu:fc56g07 Protein, APG4-C Protein, APG4C Protein, AUTL1 Protein, AUTL3 Protein, Apg4-C Protein, Apg4c Protein, Atg4cl Protein, Autl1 Protein, autophagy related 4C cysteine peptidase Protein, autophagy related 4C, cysteine peptidase Protein, cysteine protease ATG4C Protein, ATG4C Protein, atg4c Protein, Tsp_15996 Protein, Atg4c Protein
    Background

    Background: Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide.

    Synonym: Cysteine Protease ATG4C, AUT-Like 3 Cysteine Endopeptidase, Autophagin-3, Autophagy-Related Cysteine Endopeptidase 3, Autophagy-Related Protein 4 homolog C, ATG4C, APG4C, AUTL1, AUTL3

    Molecular Weight
    53.6 kDa
    UniProt
    Q96DT6
    Pathways
    Autophagy
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