B3GNT1 Protein (His tag)

Catalog No. ABIN7318190

Product Details

Target: B3GNT1 (UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 1 (B3GNT1))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This B3GNT1 protein is labelled with His tag.

Purpose: Recombinant Human B4GAT1/B3GNT1 Protein (His Tag)

Sequence: Asp43-Cys415

Characteristics: Recombinant Human N-Acetyllactosaminide beta-1,3-N-Acetylglucosaminyltransferase is produced by our Mammalian expression system and the target gene encoding Asp43-Cys415 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: B3GNT1 (UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 1 (B3GNT1))

Alternative Name: B4GAT1/B3GNT1 (B3GNT1 Products)

Synonyms: B3GN-T2 Protein, B3GNT Protein, B3GNT-2 Protein, B3GNT1 Protein, BETA3GNT Protein, BGNT2 Protein, BGnT-2 Protein, B3GNT2 Protein, B3GN-T1 Protein, B3GNT6 Protein, BETA3GNTI Protein, MDDGA13 Protein, iGAT Protein, iGNT Protein, 1500032M01Rik Protein, B3gnt6 Protein, BETA3GNT1 Protein, B3gnt1 Protein, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Protein, beta-1,4-glucuronyltransferase 1 Protein, B3GNT2 Protein, B4GAT1 Protein, B4gat1 Protein

Background:

Background: N-Acetyllactosaminide β-1,3-N-Acetylglucosaminyltransferase (B3GNT1) is a member of the β-1,3-N-Acetylglucosaminyltransferase family. B3GNT1 is a single-pass type II membrane protein and widely expressed in many tissues. B3GNT1 can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans. B3GNT1 is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood group i antigen. It can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans.

Synonym: N-Acetyllactosaminide Beta-1,3-N-Acetylglucosaminyltransferase, I-Beta-1,3-N-Acetylglucosaminyltransferase, iGnT, Poly-N-Acetyllactosamine Extension Enzyme, UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 1, B3GNT1, B3GNT6

Molecular Weight: 43.4 kDa

UniProt: O43505

Pathways: Glycosaminoglycan Metabolic Process