BTN3A3 Protein (Fc Tag)

Catalog No. ABIN7317245

Product Details

Target: BTN3A3 (butyrophilin, Subfamily 3, Member A3 (BTN3A3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This BTN3A3 protein is labelled with Fc Tag.

Purpose: Recombinant Human BTN3A3 Protein (Fc Tag)

Sequence: Met 1-Trp248

Characteristics: A DNA sequence encoding the human BTN3A3 (O00478-1) (Met1-Trp248) was fused with Fc region of mouse IgG at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: BTN3A3 (butyrophilin, Subfamily 3, Member A3 (BTN3A3))

Alternative Name: BTN3A3 (BTN3A3 Products)

Synonyms: Btn3a3 Protein, EG632126 Protein, NG11 Protein, BTF3 Protein, butyrophilin-like 4 Protein, butyrophilin subfamily 3 member A3 Protein, butyrophilin, subfamily 3, member A3 Protein, Btnl4 Protein, BTN3A3 Protein

Background:

Background: Tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the ductal epithelium of the prostate and parotid glands. TNFRSF19/TROY expression is detected in some adenocarcinoma cell lines that arise from this tissue. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. TNFRSF19/TROY is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. TNFRSF19/TROY was negatively regulated by adipogenic transcription factor CCAAT/enhancer-binding proteins (C/EBP). TNFRSF19 signals activation of the Jnk pathway and induces cell death. Overexpression of TNFRSF19 also signals NFB activation, comparable and similar to that by p75NGFR. TNFRSF19/TROY is capable of activating key signaling pathways of the TNF receptor family, and its predominant expression patterns suggest that it plays a role in the growth and regulation of epithelial tissues.

Synonym: Butyrophilin subfamily 3 member A3,BTN3A3,BTF3,BTN3.3

Molecular Weight: 50 kDa