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C1D Protein (GST tag)

C1D Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317380
  • Target See all C1D Proteins
    C1D (C1D Nuclear Receptor Corepressor (C1D))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This C1D protein is labelled with GST tag.
    Purpose
    Recombinant Human C1D Protein (GST Tag)
    Sequence
    Met 1-Ser 141
    Characteristics
    A DNA sequence encoding the human C1D (Q13901) (Met 1-Ser 141) was fused with the GST tag at the N-terminus.
    Purity
    > 80 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product C1D Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.5
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    C1D (C1D Nuclear Receptor Corepressor (C1D))
    Alternative Name
    C1D (C1D Products)
    Synonyms
    LRP1 Protein, SUN-CoR Protein, SUNCOR Protein, hC1D Protein, 1110036E10Rik Protein, AI875855 Protein, zgc:103509 Protein, RGD1560600 Protein, C1D nuclear receptor corepressor Protein, C1D nuclear receptor corepressor L homeolog Protein, C1D nuclear receptor co-repressor Protein, C1D Protein, c1d Protein, c1d.L Protein, C1d Protein
    Background

    Background: C1D nuclear receptor corepressor belongs to the C1D family. It is a DNA binding and apoptosis-inducing protein.C1D nuclear receptor corepressorinteracts with TSNAX and DNA-PKcs. It acts as a corepressor for the thyroid hormone receptor. It is thought that C1D nuclear receptor corepressor regulates TRAX/Translin complex formation. It is expressed in kidney, heart, brain, spleen, lung, testis, liver and small intestine. It plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA, this function may include MPHOSPH6. It potentiates transcriptional repression by NR1D1 and THRB. C1D nuclear receptor corepressorcan activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. It also can induce apoptosis in a p53/TP53 dependent manner.

    Synonym: hC1D,LRP1,Rrp47,SUN-CoR,SUNCOR

    Molecular Weight
    43.2 kDa
    UniProt
    Q13901
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