CNPY4 Protein (His tag)

Catalog No. ABIN7317257

Product Details

Target: CNPY4 (Canopy 4 Homolog (CNPY4))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CNPY4 protein is labelled with His tag.

Purpose: Recombinant Human CNPY4 Protein (His Tag)

Sequence: Met 1-Leu248

Characteristics: A DNA sequence encoding the human CNPY4 (Q8N129) (Met1-Leu248) was expressed with a polyhistidine tag at the C-terminus.

Purity: > 85 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CNPY4 (Canopy 4 Homolog (CNPY4))

Alternative Name: CNPY4 (CNPY4 Products)

Synonyms: 2610019P18Rik Protein, CNPY Protein, PRAT4B Protein, canopy FGF signaling regulator 4 Protein, Cnpy4 Protein, CNPY4 Protein

Background:

Background: CNPY4 belongs to the canopy family. CNPY4 interacts with toll-like receptor 4 (TLR4) and plays a role in the regulation of the cell surface expression of TLR4. Toll-like receptors (TLRs) recognize microbial products and induce immune responses. Lipopolysaccharide is recognized by the receptor complex consisting of TLR4 and MD-2. As CNPY4, PRAT4B also regulates cell surface expression of TLR4. PRAT4B has a signal peptide followed by a mature peptide. It is associated with the hypoglycosylated, immature form of TLR4 but not with MD-2 or TLR2.

Synonym: PRAT4B

Molecular Weight: 27.4 kDa

UniProt: Q8N129